Awards, Honors, and Leadership positions
1. Recipient of the ASRM/Organon grant in Reproductive Medicine, 2004-2006
2. Recipient of the Research Scientist Development Program Award, 2005-2009, a K12 grant from the NIH/NICHD
3. Co-Investigator, Development and Testing of ERE-Targeting Molecules for Breast Cancer Therapy, RO1-CA129424-01A1 (2008-2011)
4. The Appointments and Promotions Committee of the Department of Gynecology and Obstetrics, appointed for 2007-2009
Professional Societies and Memberships
American Society for Reproductive Medicine
American Institute of Ultrasound in Medicine
Society for Gynecologic Investigation
Fellow of the American College of Obstetricians and Gynecologists
Georgia Obstetrical and Gynecological Society
Research Focus and Special Interests
Dr. Kallen's research focuses on the cellular and molecular biology of steroid hormone-mediated gene regulation. In particular, his work explores the multiple pathways in which estrogens exert their effects on target tissues, the tissue-specific responses to estrogen agonists and antagonists; and investigates how these effects are modulated in health and in human disease. Insights gathered from this work may provide new avenues of treatment for conditions such as breast cancer, endometrial cancer, and osteoporosis. This work is supported by a grant from the NICHD as well as a grant from the American Society for Reproductive Medicine.
Selected Publications
Kallen, C. B. †, Hua, S. †, Dhar, R., Baquero, M. T., Mason, C., Shah, P.K., Liu, J., Khramtsov, A., Tretiakova, M. S., Krausz, T. N., Olopade, O. I., Rimm, D. L., and Kevin P. White (2008). Genomic Analysis of Estrogen Cascade Reveals a Histone Variant H2A.Z Associated with Breast Cancer Progression. (†Equal Contributors) Molecular Systems Biology, 4(188), 1-14.
Brahma K. P. and Kallen C. B. (2008) Ovarian hyperstimulation following a short course of an oral contraceptive in a patient with premature ovarian failure. Fertility and Sterility, in press.
Nanes, MS and Kallen CB. (2008). Osteoporosis. Common Errors in Obstetrics and Gynecology (ed. Carla Roberts), Book Chapter in press.
Kallen, CB (2004). Steroid Hormone Synthesis in Pregnancy. Obstetrics and Gynecology Clinics of North America. 31(4):795-816.
Kallen CB, Arici A (2003). Immune testing in fertility practice: truth or deception? Current Opinion in Obstetrics and Gynecology, 2003, 15:225-231.