Current Grants

Kevin A. Ault, MD

Title

Purpose

Sponsor

Genomic Tools for Studying the Ecology of the Human Vaginal Microflora

The major goal of this protocol is to develop microarray based tools to study the ecology of the human vagina. Dr. Ault is the Emory Principal Investigator.

Enrolling participants

University of Maryland/

NIH     

Clinical Evaluation of the APTIMA HPV Assay on the TIGRIS DTS System

The primary goal of this study is to evaluate a new molecular test that could be used to detect high-risk human papilloma virus (HPV).

GEN-PROBE, INC

A Randomized, International, Double-Blind Controlled with GARDASIL, Dose Ranging, Tolerability, Immunogenicity, and Efficacy Study of a Multivalent HPV  Virus-Like Particle (VLP) Vaccine Administered to 16-26 Year Old Women

This study will assess the efficacy of a new formulation of the HPV vaccine.

Merck & Company, Inc.

Merck-GARDASIL Girls on Guard

This is a project to increase awareness in adolescent women about the prevention of cervical cancer. Dr. Ault serves as a Co-investigator on this project.

Merck & Company, Inc

(PI-R. DiClemente)

Sarah L. Berga, MD

Title

Purpose

Sponsor

Cognitive Impairment Related to Anastrozole Use in Women

This project will explore the potential mediating effects of changes in reproductive hormone levels on cognitive function in women with breast cancer that may occur as a consequence of anastrozole therapy. 

University of Pittsburgh/ NIH/NCI

(PI-C. Bender)

Serotonin-1A Receptor Binding in Postpartum Depression

The goal of this project is to elucidate neurobiological mechanisms of post partum depression using novel imaging technologies (PET) of the serotonergic system.

University of Pittsburgh/ NIH/NIMH

(PI-E. Moses-Kolko)

Role of Serotonin in Mediating Stress-Induced Infertility

The primary goal of this proposal will be to determine the mechanisms by which common life stress impair reproductive activity.  Dr. Berga heads the human subjects aim of this project and is looking at the role of the brain chemical serotonin in stress-induced anovulation.

Enrolling Participants

Oregon Health and Sciences University/ NIH/NICHD

(PI-J. Cameron)

Carrie A. Cwiak, MD, MPH

Title

Purpose

Sponsor

Plan B Actual Use Study

Goal is to evaluate level of patients understanding and ability to correctly follow package instructions for product use.

Enrolling Participants

Duramed

Lisa C. Flowers, MD

Title

Purpose

Sponsor

Con Amor Aprendenos, With Love We Learn

This train the trainer project is an innovative, culturally sensitive educational program focused on Latino families. Our goal is to provide information about HPV and cervical cancer, elucidate the myths and enable participants to take charge of their own health.

Prevent Cancer.Org

A Phase I Study of the Safety and Tolerability of Curcumin Administered Intravaginally in Subjects with Severe Cervical Dysplasia

This pilot study has been funded by the EMCF to perform a mini pilot study to evaluate safety of topical curcumin in a limited number of women with severe cervical dysplasia.

Enrolling Participants

Emory Medical Care Foundation

Marion Howard, PhD

Title

Purpose

Sponsor

 Office of Adolescent Pregnancy Programs: Population Affairs

Caleb B. Kallen, MD, PhD

Title

Purpose

Sponsor

Reproductive Scientist Development Award-Phase II              

Funding provided by this award supports Dr. Kallen in developing an independent research focus centering on the Genome-wide Identification of DNA-binding sites for the Estrogen Receptor.  Specifically, Dr. Kallen is pursuing the characterization of alternative pathways of estrogen signaling and analysis of cell type specific and promoter-specific determinants of estrogen effects.

Burroughs Welcome Fund/

American Society of Reproductive Medicine                    

Melissa Kottke, MD, MPH

Title

Purpose

Sponsor

Atlanta-Clinical and Translational Science Institute

(A-CTSI)

The A-CTSI is an inter-institutional magnet that concentrates basic, translational, and clinical investigators, community clinicians, professional societies, and industry collaborators in dynamic clinical and translational research projects. Emory has engaged two of its close academic partners in metropolitan Atlanta - Morehouse School of Medicine and Georgia Institute of Technology. Dr. Kottke serves as a member of the Community Engagement in Research Program that seeks to improve translation of bench science to clinical practice and community impact.

NIH/NCRR

(Stephens)

Celebration, Building Healthy Teen Relationships

This project aims to reduce teen dating violence.

Robert Wood Johnson Foundation

Centering Sex Education

The goal of this project is to take a fresh look at sex education in the US.

Ford Foundation                 

Sharmila Makhija, MD

Title

Purpose

Sponsor

Georgia Cancer Coalition, Distinguished Cancer Clinicians and Scientists Award

Major goals will be to leverage this funding to support innovative translational research and training programs, in women's cancer, and in particular cancers of the ovary, cervix, and endometrium.

Georgia Cancer Coalition

 Neil Sidell, PhD

Title

Purpose

Sponsor

Retinoid effects on inflammation and cell growth associated with endometriosis 

The overall goal of this project is to understand how retinoids may be used to treat endometriosis. The information gained from these studies will lead to a new appreciation of the cause(s) of endometriosis, and the creation of new treatment modalities. 

NIH/NICHD

Development and Testing of ERE-Targeting Molecules for Breast Cancer Therapy

In this grant small molecules which specifically target regions of the DNA that are effected by the hormone estrogen are being evaluated for potential as drug candidates.  

NIH/NCI

Development of Nuclear Antioxidants for the Treatment of Endometriosis

The overall goal of this exploratory grant is to develop new compounds and understand their mode of action against endometrial cell growth, and test their efficacy in an in vivo animal model of endometriosis.  

NIH/NICHD

Robert N. Taylor, MD, PhD

Title

Purpose

Sponsor

Effects of Dienogest on Chemokine, Angiogenic, and Neurotropic Markers in Endometriosis Cells

The aim of the proposal is to establish whether and how Dienogest treatment of normal and eutopic endometriosis stromal cells in vitro modulates RANTES, VEGF, and/or nerve growth factor (NGF) gene and protein expression.

Bayer Schering

Atlanta-Clinical and Translational Science Institute (A-CTSI)

The Atlanta Clinical and Translational Science Institute (A-CTSI) is an inter-institutional magnet that concentrates basic, translational, and clinical investigators, community clinicians, professional societies, and industry collaborators in dynamic clinical and translational research projects. Emory has engaged two of its close academic partners in metropolitan Atlanta - Morehouse School of Medicine and Georgia Institute of Technology. Dr. Taylor serves as a co-investigator, member of the Leadership Committee, and as Director of the Pilot and Collaborative Translational and Clinical Studies (PiCo-TraCS) Program

NCRR

(Stephens)

Hormone-Regulated Pathways Controlling Implantation and Fertility

(Project IV: Endometriosis as a Clinical Model of Predecidual Dysfunction)

This project is part of a larger grant from the NICHD-Specialized Cooperative Center Program of Reproduction Research (SCCPRR).  The goal of Project IV is to investigate the roles of vascular endothelial growth factor (VEGF) and connexin (Cx)43 in the regulation of human endometrial decidualization. Dr. Taylor serves as the Project principal investigator.

University of Illinois Urbana/ NIH/NICHD (Bagchi)